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Potential predictor of peak aerobic capacity in subacute stroke patients.

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Alternative Title
아급성기 뇌졸중 환자에서 최대 유산소 능력의 잠재적 예측 인자
Abstract
목적: 본 연구는 아급성기 뇌졸중 환자의 균형 기능에 따른 임상적 결과물들의 상관성을 조사하고, 뇌졸중 초기의 최대 유산소 능력의 잠재적 예측인자가 무엇인지를 알아보고자 하였다.
방법: 본 연구는 총 83명 (평균 나이: 62.95 ± 13.9세)의 아급성기 뇌졸중 환자가 모집되었다. 보행 능력은 보행 속도 (10미터 걷기 속도: 10MWD)와 보행 지구력 (6분 걷기 거리: 6MWD)을 사용하였고, 균형 기능은 한글판 버그균형검사 (K-BBS)로 평가하였다. 양측 무릎 폄 근 및 굽힘 근은 등운동성 동력계로 측정하였다. 심혈관계 체력은 호기가스분석기로 평가하였고, 신체 조성은 생체 전기 임피던스 분석 장비로 측정하였다.
결과: 후진 모델의 선형 회귀 분석에서, 모든 환자들에서 마비측 등척성 무릎 폄 근력 (𝑝 < 0.001), 체지방 (𝑝 = 0.005), 10 미터 걷기 속도 (𝑝 < 0.001)는 최대 유산소 능력의 독립적인 예후인자였다 (수정된 R제곱 = 0.449). 또한 기능적 결과물에서 독립적 보행 여부에 따른 두 그룹 사이에 유의한 차이가 나타났다.
결론: 우리의 연구 결과에서는 균형 기능에 따라서 마비측 폄 근력과 굽힘 근력, 보행 속도, 보행 지구력, 최대 유산소 능력에 유의한 차이가 있음이 나타났으며, 최대 유산소 능력의 중요한 결정인자는 마비측 무릎 폄 근력과 보행 속도, 체지방임을 알 수 있었다. 그러므로, 뇌졸중 초기 회복 단계에서의 치료적 접근은 보행 속도 향상과 마비측 무릎 폄 근력에 초점을 맞춰야 할 것으로 사료된다.
Objective: To investigate the potential predictors of peak aerobic capacity in subacute stroke patients among body composition, balance function, walking capacity, and lower limb muscle strengths, and to compare the clinical functional outcomes with respect to balance function and gender.
Methods: This study was a descriptive, observational, cross-sectional study. Eighty-three subacute stroke patients were enrolled in the study (47 males and 36 females; mean age: 62.95 ± 13.9 years). Gait capacity was assessed by gait velocity (10 m walk velocity: 10MWV) and gait endurance (6 minute walk distance: 6MWD). Balance function was evaluated with the Korean version of the Berg Balance Scale (K-BBS). The isometric muscle strengths of bilateral knee flexors and extensors were measured with an isokinetic dynamometer. Cardiovascular fitness was evaluated with an expired gas analyzer. Body composition was measured with a bioelectrical impedance analysis device. We attempted to identify the major determinants of peak aerobic capacity in subacute stroke patients and to compare clinical functional outcomes with respect to balance function and gender.
Results: In backward linear regression analyses, paretic isometric extensor strength (𝑝 < 0.001), fat mass (𝑝 = 0.005), and 10MWV (𝑝 < 0.001) were independent predictors of peak aerobic capacity (adjusted R^(2)=0.449) in all patients. In addition, VO_(2peak), K-BBS, 10MWV, 6MWD, and paretic knee extensor and flexor strength significantly differed between the dependent and independent ambulatory groups (𝑝 < 0.05). Muscle mass, both knee extensor and flexor strength, and VO_(2peak) significantly differed between males and females (𝑝 < 0.05).
Conclusions: Our results confirmed that paretic knee extensor strength, gait velocity, and fat mass were major determinants of peak aerobic capacity in subacute stroke patients. Therefore, therapeutic approaches should focus on improving gait velocity and paretic knee extensor strength and on managing fat mass in the early stages of recovery from stroke.
Author(s)
김지현
Issued Date
2017
Awarded Date
2017. 2
Type
Dissertation
URI
http://dcoll.jejunu.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000008039
Alternative Author(s)
Ji-Hyun Kim
Department
대학원 의학과
Advisor
한은영
Table Of Contents
ABSTRACT . Ⅰ
CONTENTS . Ⅲ
LIST OF TABLES Ⅴ
LIST OF FIGURES Ⅵ
LIST OF ABBREVIATIONS Ⅶ
Ⅰ. INTRODUCTION 1
Ⅱ. METHODS 3
1. Participants 3
2. Bioelectrical impedance analysis and anthropometric measurements 4
3. Measurements of physical performance 4
4. Statistical analysis 8
Ⅲ. RESULTS 9
1. Baseline demographic and stroke-related data 9
2. Gait, balance, knee muscle strength, and cardiovascular fitness 10
3. Relationships between cardiovascular fitness, knee muscle strength, gait performance, balance function, body composition, and predictors of peak aerobic capacity 10
4. Functions of gait, balance, knee muscle strength, and cardiovascular fitness between the dependent ambulatory and independent ambulatory groups 18
5. Functions of gait, balance, knee muscle strength, body composition and cardiovascular fitness according to gender 20
Ⅳ. DISCUSSION 21
Ⅴ. STRENGTHS AND LIMITATION 24
Ⅵ. CONCLUSION 25
Ⅶ. REFERENCES 26
Ⅷ. ABSTRACT IN KOREAN 32
Ⅸ. APPENDICIES 34
Degree
Master
Publisher
제주대학교 일반대학원
Citation
김지현. (2017). Potential predictor of peak aerobic capacity in subacute stroke patients.
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General Graduate School > Medicine
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